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Most
synthetic organic chemicals are made from oil.
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Organic
solvents, as the name suggests, are used to dissolve other
substances.
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Phthalates
and bisphenol A are used in the production of a range of consumer
products.
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One
large group of synthetic organic chemicals is of particular concern
in public health because the chemicals are both persistent in the
environment and toxic to humans.
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Polychlorinated
biphenyls (PCBs), in which chlorine atoms are substituted for
hydrogen atoms, were manufactured mainly as insulating material for
electrical equipment. U.S. production stopped in 1977. Dioxins were
created as byproducts of the manufacture of PCBs.
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Polybrominated
diphenyl ethers (PBDEs), in which bromine atoms are substituted for
hydrogen atoms, are manufactured and used as flame-retardant
chemicals.
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Perfluorochemicals
(PFCs), in which fluorine atoms are substituted for hydrogen atoms,
have been used in the production of stain- or water-resistant
coatings.
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Another
group of chlorine-containing synthetic organic compounds affects
human health indirectly by upsetting the natural dynamic equilibrium
among oxygen atoms(O), molecular oxygen (O2), and ozone (O3) in the
stratosphere—specifically, by tipping the balance toward the
destruction of ozone.
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Toxics
use reduction is a preventive approach to chemical hazards.
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The
six metals described in the text—inorganic lead, mercury
(elemental and inorganic), arsenic, cadmium, chromium, and
beryllium—have substantial public health impacts, especially in
the workplace.
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This
new technology takes advantage of the fact that the physical and
chemical properties of a given material are sometimes different when
the material is formed into extremely fine particles.
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Workers
generally have much higher exposures to particles and fibers than
the general public does.
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There
are parallels between the stories of asbestos and cotton as
respiratory hazards in the workplace.
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Mechanical
hazards in the workplace are usually more visible than harmful
substances. They are also more fatal.
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Exposure
to noise in the workplace can cause temporary or permanent hearing
loss and has been linked to coronary heart disease and heart attack.
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Shift
work that increases workers’ exposure to light during the
biological night is now deemed likely to increase the risk of
cancer.
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Certain
organic chemicals, metals, and physical agents in the workplace are
known to cause asthma in workers; that is, occupational asthma.
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At
both the national and international scales, socially disadvantaged
populations bear a heavier burden of exposure to industrial wastes;
in the more developed countries, social differences in exposure to
newer industrial chemicals in household or consumer products (e.g.,
BPA, PFCs, and PBDEs) are more complex.
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A
framework exists for managing the international trade in hazardous
wastes.
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Examining
the U.S. regulatory framework in stepwise fashion, moving generally
upstream in a conceptual sense, highlights missed opportunities for
preventing public health impacts of industry.